SCHEMBL7300860

SCHEMBL7300860

O=C(O)CC(O)(Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 8/20 0.56
ALDH1A1 P00352 1/20 0.54
LMNA P02545 3/20 0.53
CYP1A2 P05177 2/20 0.53
KDM4E B2RXH2 2/20 0.53
MEN1 O00255 1/20 0.53
CYP2D6 P10635 1/20 0.53
KMT2A Q03164 1/20 0.53
HIF1A Q16665 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
FDPS P14324 1/20 0.46
CYP2C19 P33261 2/20 0.45
CYP2C9 P11712 1/20 0.45
AKR1B1 P15121 1/20 0.45
KEAP1 Q14145 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941763 0.98 SLC13A5 (0.54) SLC13A5ALDH1A1LMNACYP1A2KDM4E
SCHEMBL419615 0.87 SMN1; SMN2 (0.59) SLC13A5ALDH1A1LMNACYP1A2KDM4E
Eucomic Acid SCHEMBL23355983 0.85 BLM (0.51) SLC13A5ALDH1A1LMNACYP1A2KDM4E
SCHEMBL559624 0.85 SMN1; SMN2 (0.48) SLC13A5ALDH1A1LMNACYP1A2KDM4E
SCHEMBL9554586 0.85 SMN1; SMN2 (0.53) SLC13A5ALDH1A1LMNACYP1A2KDM4E
Eucomic Acid SCHEMBL12466852 0.85 BLM (0.51) SLC13A5ALDH1A1LMNACYP1A2KDM4E
SCHEMBL9554595 0.85 SMN1; SMN2 (0.53) SLC13A5ALDH1A1LMNACYP1A2KDM4E
Citric Acid SCHEMBL27471655 0.82 AKR1B1 (0.65) SLC13A5ALDH1A1LMNACYP1A2KDM4E
Citric Acid SCHEMBL8861325 0.82 ALDH1A1 (0.58) SLC13A5ALDH1A1LMNACYP1A2KDM4E
SCHEMBL3730337 0.82 SMN1; SMN2 (0.53) SLC13A5ALDH1A1LMNACYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521907-B1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-10921489-B2 Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens MITSUI CHEMICALS, INC. (JP) 2021-02-16 US disclosed
CN-108690104-B Glucose oxybenzyl ester compounds, and preparation method and application thereof 北京理工大学 2020-11-20 CN disclosed
CN-108530496-B Gluconoxybenzyl malate compounds for treating liver injury, and preparation method and application thereof 北京理工大学 2020-10-30 CN disclosed
EP-3351564-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM COMPOSITION MITSUI CHEMICALS INC (JP) 2020-04-15 EP disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
EP-3521907-A1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION Mitsui Chemicals, Inc. (JP) 2019-08-07 EP disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20190211258-A1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2019-07-11 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
CN-105452310-A Polymerizable composition for high-refractive-index optical material and method for producing high-refractive-index optical material KOC SOLUTION CO LTD 2016-03-30 CN disclosed
CN-104583252-A Polymerizable composition for epoxy acrylic optical material and method for producing epoxy acrylic optical material KOC SOLUTION CO LTD 2015-04-29 CN disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed
WO-2014035125-A1 POLYMERIZATION COMPOSITION FOR EPOXY ACRYLIC OPTICAL MATERIAL AND METHOD FOR MANUFACTURING EPOXY ACRYLIC OPTICAL MATERIAL 주식회사 케이오씨솔루션 (KR) 2014-03-06 WO disclosed
WO-2014027849-A1 POLYMERIZABLE COMPOSITION FOR EPOXY ACRYLIC OPTICAL MATERIAL, AND METHOD FOR PREPARING EPOXY ACRYLIC OPTICAL MATERIAL 주식회사 케이오씨솔루션 (KR) 2014-02-20 WO disclosed
EP-0366669-A1 MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES THE UPJOHN COMPANY (US) 1990-05-09 EP disclosed
EP-0341602-A2 Renin-inhibiting functionalized peptidyl aminodiols and - triols ABBOTT LABORATORIES (US) 1989-11-15 EP disclosed
WO-1989000161-A1 MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES THE UPJOHN COMPANY (US) 1989-01-12 WO disclosed
EP-0101944-A1 Immunomodulators containing as the active ingredient alpha-benzyl malic acid MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1984-03-07 EP disclosed