Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9501139 | 0.81 | SCN5A (0.53) | SCN5ACACNA1BSLC6A3TBXA2RMEN1 | |
| SCHEMBL361963 | 0.78 | MAPT (0.43) | MEN1KMT2ACYP2C19 | |
| SCHEMBL10257970 | 0.78 | MAPT (0.40) | MEN1KMT2ACYP2C19 | |
| SCHEMBL5026067 | 0.77 | CYP3A4 (0.58) | LTA4HCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL15094479 | 0.76 | CYP1A2 (0.40) | LTA4HCACNA1BCYP3A4CYP2D6FAAH | |
| SCHEMBL6006300 | 0.76 | LTA4H (0.56) | LTA4HCYP3A4CYP2D6KMT2ASMN1; SMN2 | |
| SCHEMBL3735417 | 0.75 | CA12 (0.51) | LTA4HMEN1KMT2ASMN1; SMN2CYP2C19 | |
| Bromide SCHEMBL11583932 | 0.74 | SCN5A (0.55) | SCN5ACACNA1BSLC6A3CYP3A4CYP2D6 | |
| SCHEMBL3641329 | 0.74 | HPGD (0.55) | CYP3A4CYP2D6TSHRMAPK1MEN1 | |
| SCHEMBL10291728 | 0.74 | MAPT (0.38) | MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190930-A | Calcium metabolism disorder | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |