Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555377 | 0.88 | KDM4E (0.57) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555418 | 0.86 | PTGDR2 (0.60) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555733 | 0.85 | PTGDR2 (0.59) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555373 | 0.85 | PTGDR2 (0.58) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555350 | 0.85 | KMT2A (0.50) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555535 | 0.84 | PTGDR2 (0.57) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555332 | 0.83 | KDM4E (0.47) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL3065774 | 0.82 | PTGDR2 (0.56) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2580648 | 0.82 | KDM4E (0.62) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9555280 | 0.82 | KMT2A (0.63) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182402-A | 2-Phenylthiazolecarboxylic Acids and Esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-26 | — | — | US | disclosed |
| US-5084083-A | Phenylthiazolecarboxylic acid derivative herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| EP-0368592-A1 | Herbicidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-16 | — | — | EP | disclosed |