Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.48 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4462240 | 0.88 | KDM4E (0.57) | PTGDR2KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL3537226 | 0.86 | PTGDR2 (0.56) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9555373 | 0.85 | PTGDR2 (0.58) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13710251 | 0.84 | SHMT1 (0.46) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9555535 | 0.84 | PTGDR2 (0.57) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL4905523 | 0.83 | MAPT (0.56) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2580648 | 0.82 | KDM4E (0.62) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL9555341 | 0.82 | PTGDR2 (0.59) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL13710237 | 0.82 | SHMT1 (0.49) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL3257464 | 0.82 | PTPN11 (0.47) | PTGDR2KDM4EALDH1A1CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225211-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | DU PONT (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| EP-2225211-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-08 | — | — | EP | disclosed |
| US-7566731-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2009-07-28 | — | — | US | disclosed |
| WO-2009086041-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| EP-1212299-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA UK LTD (GB) | 2009-04-08 | — | — | EP | disclosed |
| US-7420062-B2 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE, AG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |
| US-7141533-B2 | Hetaryl-substituted heterocycles | BAYER CROPSCIENCE AG (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20060084576-A1 | 2-(Chloro),4-(ethoxycarbonyl-isoprop-2,2-ylene-isoprop-2,2-ylene-oxycarbonyl-methyl),5-(methyl-thiazole; bactericides; herbicides; insecticides; fungicides; nematocides; algicides; molluscicides; construction materials; wood; clay; alkali resistance | FISCHER REINER | 2006-04-20 | — | — | US | disclosed |
| US-7026341-B2 | Hetaryl substituted homotetramic and homotetronic acids and their use thereof as pesticides | BAYER CROPSCIENCE AG (DE) | 2006-04-11 | — | — | US | disclosed |
| US-20050250792-A1 | Substituted piperidine compounds useful as modulators of chemokine receptor activity | MERRILL LYNCH CAPITAL, A DIVISION OF MERRILL LYNCH BUSINESS FINANCIAL SERVICES, INC. AS ADMINISTRATIVE AGENT | 2005-11-10 | — | — | US | disclosed |
| US-6903085-B1 | Substituted piperidine compounds useful as modulators of chemokine receptor activity | ASTRAZENECA, AB (CH) | 2005-06-07 | — | — | US | disclosed |
| US-20040220243-A1 | Hetaryl-substituted heterocycles | FISCHER REINER (DE) | 2004-11-04 | — | — | US | disclosed |
| US-6767864-B2 | PESTICIDES, HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2004-07-27 | — | — | US | disclosed |
| US-20040097558-A1 | Hetaryl substituted homotetramic and homtetronic acids and the use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-05-20 | — | — | US | disclosed |
| US-20040009877-A1 | HETARYL-SUBSTITUTED HETEROCYCLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-01-15 | — | — | US | disclosed |
| EP-1212299-A1 | SUBSTITUTED PIPERIDINE COMPOUNDS USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca UK Limited (GB) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001014333-A1 | SUBSTITUTED PIPERIDINE COMPOUNDS USEFUL AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA UK LIMITED (GB) | 2001-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | PTGDR2 180/4885KDM4E 2418/4885ALDH1A1 769/4885 |
| US-20040009877-A1 | HETARYL-SUBSTITUTED HETEROCYCLES | DDT, CYP1B1, CYP4B1 | PTGDR2 466/4885KDM4E 1905/4885ALDH1A1 308/4885 |
| US-20040220243-A1 | Hetaryl-substituted heterocycles | CYP1B1, DDT, CYP1A1 | PTGDR2 551/4885KDM4E 2517/4885ALDH1A1 114/4885 |
| US-20050250792-A1 | Substituted piperidine compounds useful as modulators of chemokine receptor activity | CXCR4, CXCR1, CXCR3 | PTGDR2 112/4885KDM4E 2699/4885ALDH1A1 1952/4885 |
| US-20040097558-A1 | Hetaryl substituted homotetramic and homtetronic acids and the use thereof as pesticides | CYP1B1, CYP1A1, CYP2B6 | PTGDR2 226/4885KDM4E 4009/4885ALDH1A1 397/4885 |
| US-20060084576-A1 | 2-(Chloro),4-(ethoxycarbonyl-isoprop-2,2-ylene-isoprop-2,2-ylene-oxycarbonyl-methyl),5-(methyl-thiazole; bactericides; herbicides; insecticides; fungicides; nematocides; algicides; molluscicides; construction materials; wood; clay; alkali resistance | DDT, CYSLTR2, LTB4R2 | PTGDR2 62/4885KDM4E 777/4885ALDH1A1 1193/4885 |
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | CYP1A1, CYP1B1, CBR3 | PTGDR2 683/4885KDM4E 2379/4885ALDH1A1 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.