Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555754 | 1.00 | NPSR1 (0.31) | NPSR1MCL1L3MBTL1 | |
| SCHEMBL9417253 | 0.87 | — | — | |
| SCHEMBL9857566 | 0.84 | — | — | |
| SCHEMBL9417141 | 0.81 | MCL1 (0.39) | MCL1L3MBTL1 | |
| SCHEMBL9674799 | 0.76 | — | — | |
| SCHEMBL9676871 | 0.75 | — | — | |
| SCHEMBL9676830 | 0.75 | — | — | |
| SCHEMBL9858217 | 0.74 | — | — | |
| SCHEMBL9417200 | 0.74 | HPRT1 (0.46) | — | |
| SCHEMBL9417136 | 0.74 | ADORA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |