Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.60 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 13/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556794 | 1.00 | IL6ST (0.60) | IL6STSTAT3IDH1NAAACHRM1 | |
| SCHEMBL9556716 | 1.00 | IL6ST (0.60) | IL6STSTAT3IDH1NAAACHRM1 | |
| SCHEMBL9556952 | 1.00 | IL6ST (0.60) | IL6STSTAT3IDH1NAAACHRM1 | |
| SCHEMBL17418485 | 0.91 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL20099031 | 0.91 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL17418481 | 0.91 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA | |
| Hydrochloric Acid SCHEMBL9557175 | 0.85 | IL6ST (0.58) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7787910 | 0.83 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL8812238 | 0.83 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL8812243 | 0.83 | IL6ST (0.64) | IL6STSTAT3IDH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242903-A | Enzyme inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| US-5095006-A | Enzyme inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0412350-A2 | Renininhibitors, procedure for their preparation and use as medicaments | BAYER AG (DE) | 1991-02-13 | — | — | EP | disclosed |