SCHEMBL9557170

SCHEMBL9557170

CCC[C@@H]1COC(=O)N1C(=O)[C@@H](Cc1ccccc1)[C@@H](O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IL6ST P40189 1/20 0.41
PPARA Q07869 1/20 0.40
FAAH O00519 1/20 0.39
CHRM1 P11229 7/20 0.38
NAAA Q02083 1/20 0.38
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
IDH1 O75874 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9556955 1.00 IL6ST (0.41) IL6STPPARAFAAHCHRM1NAAA
SCHEMBL9556799 1.00 IL6ST (0.41) IL6STPPARAFAAHCHRM1NAAA
SCHEMBL9556721 1.00 IL6ST (0.41) IL6STPPARAFAAHCHRM1NAAA
Hydrochloric Acid SCHEMBL9557176 0.85 IL6ST (0.40) IL6STPPARAFAAHCHRM1NAAA
SCHEMBL9556794 0.83 IL6ST (0.60) IL6STCHRM1NAAAIDH1
SCHEMBL9556716 0.83 IL6ST (0.60) IL6STCHRM1NAAAIDH1
SCHEMBL9557166 0.83 IL6ST (0.60) IL6STCHRM1NAAAIDH1
SCHEMBL9556952 0.83 IL6ST (0.60) IL6STCHRM1NAAAIDH1
SCHEMBL24252139 0.78 PPARA (0.47) IL6STPPARAFAAHNAAAIDH1
SCHEMBL13719446 0.77 PPARA (0.48) IL6STPPARAFAAHNAAAIDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5242903-A Enzyme inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1993-09-07 US disclosed
US-5095006-A Enzyme inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed