SCHEMBL95573

SCHEMBL95573

[CH2]CCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28000694 0.97 DUT (0.33) DUT
SCHEMBL94712 0.85 DUT (0.39) DUT
SCHEMBL97324 0.83 DUT (0.38) DUT
SCHEMBL11580466 0.83 DUT (0.42) DUT
SCHEMBL97731 0.81 DUT (0.37) DUT
SCHEMBL9517441 0.81 DUT (0.37) DUT
SCHEMBL9517422 0.81 DUT (0.37) DUT
SCHEMBL7674744 0.78 DUT (0.41) DUT
SCHEMBL8063404 0.78 DUT (0.43) DUT
SCHEMBL132024 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384079-B Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-05-24 CN claimed
CN-117384079-A Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-01-12 CN claimed
CN-115536704-A Nitrogen bismuth octa-cycloalkyl bismuth compounds and synthesis method thereof 湖南大学 2022-12-30 CN claimed
CN-115093448-A Nitrogen-antimony octylene alkyl antimony derivatives and synthesis method thereof 湖南大学 2022-09-23 CN claimed
US-20050137220-A1 Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors PHARMACIA CORPORATION (US) 2005-06-23 US claimed
WO-1996040692-A1 ORGANOLITHIUM PROCESS FMC CORPORATION (US) 1996-12-19 WO claimed
EP-0670838-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-09-13 EP claimed
US-5359073-A Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists G. D. SEARLE & CO. (US) 1994-10-25 US claimed
WO-1994012500-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-06-09 WO claimed
US-5262426-A Treatment of cardiovascular disorders, antiinflammatory agents G. D. SEARLE & CO. (US) 1993-11-16 US claimed
CN-117384079-B Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-05-24 CN disclosed
CN-113227174-B Functionalized rubbers 戴纳索尔埃拉斯托默罗斯有限公司 2024-04-26 CN disclosed
CN-117384079-A Chiral N-alkyl indole compound and preparation method and application thereof 云南大学 2024-01-12 CN disclosed
CN-115260064-B Alkenyl thioether prepared by terminal alkyne high cis-form selective hydrosulfide and synthetic method thereof 湖南大学 2023-10-20 CN disclosed
CN-116848113-A Bicyclic compounds as HPK1 inhibitors and application thereof 南京再明医药有限公司 2023-10-03 CN disclosed
WO-1997045429-A1 BETA-LACTAMS F. HOFFMANN-LA ROCHE AG (CH) 1997-12-04 WO disclosed
WO-1997023520-A1 FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION FMC CORPORATION (US) 1997-07-03 WO disclosed
WO-1996040692-A1 ORGANOLITHIUM PROCESS FMC CORPORATION (US) 1996-12-19 WO disclosed
WO-1994012500-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-06-09 WO disclosed
US-5262426-A Treatment of cardiovascular disorders, antiinflammatory agents G. D. SEARLE & CO. (US) 1993-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050137220-A1 Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors MAPKAPK2, MAP4K2, MAP3K2 DUT 2363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.