Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557747 | 0.92 | CYP3A4 (0.49) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL9557511 | 0.88 | MAPT (0.49) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL9557539 | 0.86 | POLB (0.53) | ABCB1CYP3A4TP53 | |
| SCHEMBL9557267 | 0.85 | CYP3A4 (0.40) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL9557809 | 0.84 | ABCB1 (0.48) | RAB9ASMN1; SMN2HPGDABCB1 | |
| SCHEMBL9558166 | 0.84 | CYP3A4 (0.50) | RAB9ASMN1; SMN2NPC1MAPTHPGD | |
| SCHEMBL9557635 | 0.83 | CES2 (0.49) | MAPTTSHRALDH1A1 | |
| SCHEMBL9557877 | 0.83 | CES2 (0.49) | MAPTTSHRALDH1A1 | |
| SCHEMBL9557295 | 0.83 | MAPT (0.51) | RAB9ASMN1; SMN2NPC1MAPTABCB1 | |
| SCHEMBL9557598 | 0.82 | ABCB1 (0.47) | SMN1; SMN2MAPTHPGDABCB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |