Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557717 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL9557418 | 0.94 | MAPT (0.40) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL9557521 | 0.92 | ALDH1A1 (0.49) | ALDH1A1HPGDCES2CES1POLB | |
| SCHEMBL9557357 | 0.89 | HPGD (0.55) | HPGDRAB9AMEN1KMT2AHDAC6 | |
| SCHEMBL9557769 | 0.89 | ABCB1 (0.45) | ALDH1A1HPGDPOLB | |
| SCHEMBL9557211 | 0.88 | ESR1 (0.47) | ALDH1A1HPGDCES2POLBMAPT | |
| SCHEMBL9557667 | 0.87 | HPGD (0.56) | ALDH1A1HPGDNPC1RAB9AMEN1 | |
| SCHEMBL9557566 | 0.87 | HPGD (0.49) | ALDH1A1HPGDPOLBMAPTOPRM1 | |
| SCHEMBL9557442 | 0.87 | ALDH1A1 (0.45) | ALDH1A1HPGDCES2CES1POLB | |
| SCHEMBL9558150 | 0.87 | ALDH1A1 (0.45) | ALDH1A1HPGDCES2CES1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |