Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557538 | 0.87 | MAPT (0.40) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9877608 | 0.81 | MEN1 (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10780929 | 0.81 | KMT2A (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9824746 | 0.65 | POLB (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9557914 | 0.65 | HPGD (0.49) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9557612 | 0.61 | HPGD (0.42) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL25247000 | 0.61 | HPGD (0.57) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL11600504 | 0.61 | HPGD (0.61) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5644991 | 0.60 | HPGD (0.53) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL31479876 | 0.60 | HPGD (0.51) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225443-A | Lepidotera and Coleoptera insecticides to protect plants | ROHM AND HAAS COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |