Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780929 | 0.92 | KMT2A (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9824746 | 0.86 | POLB (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9557532 | 0.81 | MEN1 (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9557538 | 0.78 | MAPT (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10780937 | 0.77 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9824961 | 0.74 | SMN1; SMN2 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10718578 | 0.74 | ABCB1 (0.45) | SMN1; SMN2NPC1RAB9ALMNAHDAC1 | |
| SCHEMBL20460223 | 0.73 | ABCB1 (0.51) | ALDH1A1LMNAF2R | |
| SCHEMBL10719018 | 0.73 | POLB (0.47) | ALDH1A1HPGDLMNA | |
| SCHEMBL9877218 | 0.72 | POLB (0.58) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0245950-A2 | Insecticidal n-substituted-n' - substituted-n, n'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |