Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603609 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL3719347 | 0.83 | — | — | |
| SCHEMBL11570313 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL11570310 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL4783327 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL18790095 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL26720816 | 0.83 | EPAS1 (0.42) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL8062474 | 0.83 | EPAS1 (0.34) | EPAS1 | |
| SCHEMBL24367146 | 0.80 | EPAS1 (0.41) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 | |
| SCHEMBL24622814 | 0.80 | EPAS1 (0.41) | MBTD1L3MBTL3EPAS1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215967-A | AMINOACID DERIVATIVES INHIBITING RENIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-06-01 | — | — | US | disclosed |