SCHEMBL9558102

SCHEMBL9558102

CSc1ccc(OCc2ccc(Br)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.61
MAOB P27338 9/20 0.57
RXRA P19793 1/20 0.54
RXRB P28702 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
FFAR1 O14842 2/20 0.51
FFAR4 Q5NUL3 1/20 0.51
PTPRZ1 P23471 1/20 0.50
MAOA P21397 6/20 0.48
PPARA Q07869 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399080 0.84 APP (0.80) APPMAOBRXRARXRBCA12
SCHEMBL9558824 0.84 MAOB (0.56) APPMAOBPTPRZ1MAOAHRH3
SCHEMBL8355718 0.84 MAOB (0.56) APPMAOBPTPRZ1MAOAHRH3
SCHEMBL9558763 0.84 APP (0.62) APPMAOBFFAR1PTPRZ1
SCHEMBL9557834 0.82 MAOB (0.61) APPMAOBPTPRZ1MAOA
SCHEMBL23639432 0.81 LMNA (0.60) MAOBMAOA
SCHEMBL388096 0.81 LMNA (0.60) MAOBMAOA
SCHEMBL18429678 0.79 MAOB (0.69) APPMAOBRXRARXRBCA12
SCHEMBL14154468 0.79 APP (0.67) APPMAOBRXRARXRBCA12
SCHEMBL13929696 0.79 APP (0.67) APPMAOBRXRARXRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019548-A Basic Dye, Color Acceptor, Benzyloxyphenyl Methyl Sulfide KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-05-28 US claimed
EP-0358193-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-14 EP claimed
US-5242884-A Storage stability, antioxidant, secondary amine, basic dye KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-09-07 US disclosed
US-5019548-A Basic Dye, Color Acceptor, Benzyloxyphenyl Methyl Sulfide KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-05-28 US disclosed
EP-0358193-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-03-14 EP disclosed