SCHEMBL9558208

SCHEMBL9558208

CC(C)(COCc1ccc(F)c(Oc2ccccc2)c1)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A3 Q01959 2/20 0.39
EPHX2 P34913 2/20 0.37
LTA4H P09960 1/20 0.37
TACR1 P25103 2/20 0.37
KIF11 P52732 1/20 0.37
MAPK14 Q16539 1/20 0.36
CETP P11597 1/20 0.36
PPARG P37231 1/20 0.36
CHRM5 P08912 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR5 Q9H1C0 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
NR1H4 Q96RI1 1/20 0.34
NR3C1 P04150 1/20 0.34
AR P10275 1/20 0.34
TTR P02766 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558563 0.93 TACR1 (0.37) SLC6A4SLC6A2SLC6A3TACR1MAPK14
SCHEMBL9559005 0.92 SLC6A4 (0.38) SLC6A4SLC6A2SLC6A3EPHX2PPARG
SCHEMBL10837117 0.92 NPC1 (0.38) LTA4HTACR1MAPK14PPARGLPAR1
SCHEMBL10836475 0.91 TTR (0.38) SLC6A4SLC6A2SLC6A3TACR1MAPK14
SCHEMBL10835647 0.91 TACR1 (0.36) SLC6A4SLC6A2SLC6A3TACR1MAPK14
SCHEMBL9558183 0.91 TACR1 (0.36) SLC6A4SLC6A2SLC6A3TACR1MAPK14
SCHEMBL10836610 0.90 CETP (0.37) TACR1CETPPPARGLPAR1LPAR5
SCHEMBL10836022 0.90 TACR1 (0.36) TACR1MAPK14PPARGLPAR1LPAR5
SCHEMBL9558410 0.90 TACR1 (0.44) SLC6A4EPHX2LTA4HTACR1MAPK14
SCHEMBL10837162 0.90 TACR1 (0.36) TACR1KIF11LPAR1LPAR5TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed