SCHEMBL10836610

SCHEMBL10836610

CC(C)(COCc1ccc(F)c(Oc2ccccc2)c1)c1ccc(OC(F)(F)C(F)F)cc1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CETP P11597 16/20 0.37
KCNH2 Q12809 7/20 0.37
TACR1 P25103 1/20 0.35
PPARG P37231 1/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR5 Q9H1C0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558563 0.90 TACR1 (0.37) TACR1PPARGLPAR1LPAR5
SCHEMBL9558208 0.90 SLC6A4 (0.39) CETPTACR1PPARGLPAR1LPAR5
SCHEMBL10837117 0.89 NPC1 (0.38) TACR1PPARGLPAR1LPAR5
SCHEMBL9558183 0.88 TACR1 (0.36) KCNH2TACR1PPARGLPAR1LPAR5
SCHEMBL10836475 0.88 TTR (0.38) KCNH2TACR1PPARGLPAR1LPAR5
SCHEMBL10835647 0.88 TACR1 (0.36) TACR1PPARGLPAR1LPAR5
SCHEMBL9558277 0.87 MRGPRX4 (0.34) KCNH2TACR1PPARGLPAR1LPAR5
SCHEMBL9558410 0.87 TACR1 (0.44) TACR1PPARGLPAR1LPAR5
SCHEMBL10837667 0.87 TACR1 (0.42) TACR1LPAR1LPAR5
SCHEMBL10837106 0.87 TACR1 (0.34) CETPTACR1PPARGLPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4599362-A 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives MITSUITOATSU CHEMICALS, INC. (JP) 1986-07-08 US disclosed