SCHEMBL9558209

SCHEMBL9558209

Cc1cc(Cc2ccc(C(=O)O)cc2)cc(C)c1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.59
ALDH1A1 P00352 3/20 0.50
RXRA P19793 3/20 0.49
RXRB P28702 2/20 0.49
RXRG P48443 2/20 0.49
HMGB1 P09429 1/20 0.47
CXCL12 P48061 1/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.46
LMNA P02545 2/20 0.46
NR1H4 Q96RI1 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
NR4A1 P22736 1/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581994 0.87 HMGB1 (0.59) SRD5A2ALDH1A1HMGB1CXCL12KMT2A
SCHEMBL926497 0.86 HMGB1 (0.61) SRD5A2ALDH1A1RXRARXRBRXRG
SCHEMBL19413941 0.82 SRD5A2 (0.59) SRD5A2ALDH1A1RXRARXRBRXRG
Terephthalic Acid SCHEMBL7823824 0.81 ALDH1A1 (0.56) SRD5A2ALDH1A1RXRARXRBKMT2A
SCHEMBL9558175 0.80 KMT2A (0.49) SRD5A2ALDH1A1RXRARXRBRXRG
SCHEMBL68390 0.80 SRD5A2 (0.69) SRD5A2ALDH1A1RXRARXRBRXRG
SCHEMBL7877554 0.79 SRD5A2 (0.89) SRD5A2ALDH1A1RXRARXRBRXRG
SCHEMBL28951143 0.79 SRD5A2 (0.58) SRD5A2ALDH1A1RXRARXRBRXRG
SCHEMBL11673315 0.78 SRD5A2 (0.62) SRD5A2ALDH1A1RXRARXRBRXRG
Hydrochloric Acid SCHEMBL25188150 0.78 SRD5A2 (0.67) SRD5A2ALDH1A1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332425-B1 PROCESS FOR REFINING 1,3-DIMETHYL-2-IMIDAZOLIDINONE AND A PROCESS FOR PREPARING AN AROMATIC POLYAMIDE BY USE OF THE REFINED PRODUCT MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed
US-5075406-A Solution polymerization of polyamides in solvent purified by adsorption on magnesia, alumina, silica or mixed oxides MITSUI TOATSU CHEMICALS, INC. (JP) 1991-12-24 US disclosed
US-5011936-A Using composite salt consisting of at least two of silica, magnesia and alumina MITSUI TOATSU CHEMICALS, INC. (JP) 1991-04-30 US disclosed
US-4923951-A DIISOCYANTE, ALKALI OR ALKALINE EARTH METAL CATALYST MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1990-05-08 US disclosed
EP-0332425-A1 Process for refining 1,3-dimethyl-2-imidazolidinone and a process for preparing an aromatic polyamide by use of the refined product MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-09-13 EP disclosed
EP-0328342-A2 Process for producing aromatic polyamides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-16 EP disclosed