Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7829923 | 0.90 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL7829454 | 0.89 | HDAC1 (0.48) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL7828928 | 0.89 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL2453660 | 0.89 | PDE4B (0.44) | — | |
| SCHEMBL2460183 | 0.87 | PDE4B (0.45) | — | |
| SCHEMBL7833657 | 0.87 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL7831165 | 0.86 | HDAC6 (0.47) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL9309807 | 0.86 | HDAC1 (0.49) | HDAC1HDAC8HDAC2HDAC3HDAC10 | |
| SCHEMBL9309249 | 0.79 | PTGER2 (0.37) | HDAC1HDAC8HDAC2HDAC3HDAC6 | |
| SCHEMBL7832551 | 0.79 | HDAC1 (0.48) | HDAC1HDAC8HDAC2HDAC3HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1104033-A | — | — | None | — | — | JP | disclosed |
| US-5272180-A | Cell proliferation inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0301861-B1 | CELL PROLIFERATION INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1992-04-01 | — | — | EP | disclosed |
| JP-H01104033-A | HYDROXAMIC ACID DERIVATIVE | TAKEDA CHEM IND LTD | 1989-04-21 | — | — | JP | disclosed |
| EP-0301861-A1 | Cell proliferation inhibitors | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |