Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453660 | 0.99 | PDE4B (0.44) | PDE4BHTTNPSR1TBXAS1TBXA2R | |
| SCHEMBL7821080 | 0.89 | CDC25A (0.42) | PDE4BHTTNPSR1TBXAS1TBXA2R | |
| SCHEMBL7828948 | 0.88 | TBXAS1 (0.43) | PDE4BHTTNPSR1TBXAS1TBXA2R | |
| SCHEMBL9558902 | 0.87 | HDAC1 (0.51) | — | |
| SCHEMBL2490724 | 0.86 | TBXA2R (0.46) | TBXAS1TBXA2RFFAR1KMT2APTGFR | |
| SCHEMBL9308585 | 0.85 | TBXAS1 (0.50) | TBXAS1TBXA2R | |
| Seratrodast SCHEMBL98402 | 0.84 | TBXAS1 (0.52) | TBXAS1TBXA2R | |
| Seratrodast SCHEMBL98403 | 0.84 | TBXAS1 (0.52) | TBXAS1TBXA2R | |
| SCHEMBL9308117 | 0.84 | TBXAS1 (0.52) | TBXAS1TBXA2R | |
| SCHEMBL9391332 | 0.84 | PDE4B (0.57) | PDE4BHTTNPSR1TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534548-A | Method of treating preeclampsia | TAP PHARMACEUTICALS, INC. (US) | 1996-07-09 | — | — | US | claimed |
| WO-1995029671-A1 | BENZOQUINON ALKANOIC ACIDS FOR TREATING PREECLAMPSIA | TAP HOLDINGS INC. (US) | 1995-11-09 | — | — | WO | claimed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | claimed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | claimed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | claimed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | claimed |
| WO-2011146819-A2 | METHODS AND COMPOSITIONS FOR TREATMENT NF-κB-MEDIATED AND α7 INTEGRIN-SUPPRESSED DISEASES | DMD THERAPIES, LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | WHALEN ANNE | 2011-09-15 | — | — | US | disclosed |
| US-5534548-A | Method of treating preeclampsia | TAP PHARMACEUTICALS, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1995029671-A1 | BENZOQUINON ALKANOIC ACIDS FOR TREATING PREECLAMPSIA | TAP HOLDINGS INC. (US) | 1995-11-09 | — | — | WO | disclosed |
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224128-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY | PYGM, TNNC1, MYOF | PDE4B 122/4885HTT 694/4885NPSR1 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.