SCHEMBL9559078

SCHEMBL9559078

COc1cc(O)c2c(c1)C(=O)C(C)=C(C(C)=O)C2=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
KDM4E B2RXH2 4/20 0.60
ELANE P08246 4/20 0.60
MAPT P10636 4/20 0.60
HPGD P15428 3/20 0.60
ALOX15 P16050 2/20 0.60
GLA P06280 1/20 0.60
NFKB1 P19838 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
IDO1 P14902 1/20 0.45
CYP3A4 P08684 6/20 0.43
MAPK1 P28482 4/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 2/20 0.42
CYP1A2 P05177 2/20 0.41
ACLY P53396 2/20 0.41
POLB P06746 3/20 0.40
RECQL P46063 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16226983 0.79 ELANE (0.83) ALDH1A1KDM4EELANEMAPTHPGD
Acetic Acid SCHEMBL5810869 0.77 ALDH1A1 (0.60) ALDH1A1KDM4EELANEMAPTHPGD
SCHEMBL16226000 0.76 ELANE (0.90) ALDH1A1KDM4EELANEMAPTHPGD
SCHEMBL30140513 0.76 ELANE (0.90) ALDH1A1KDM4EELANEMAPTHPGD
SCHEMBL30583631 0.76 PPARG (0.49) ALDH1A1HPGDIDO1CYP3A4MAPK1
SCHEMBL5093803 0.75 ALDH1A1 (0.58) ALDH1A1KDM4EELANEMAPTHPGD
Physcion SCHEMBL29404320 0.75 ELANE (1.00) ALDH1A1KDM4EELANEMAPTHPGD
Physcion SCHEMBL486155 0.75 ELANE (1.00) ALDH1A1KDM4EELANEMAPTHPGD
Physcion SCHEMBL30425832 0.75 ELANE (1.00) ALDH1A1KDM4EELANEMAPTHPGD
SCHEMBL16225846 0.75 ELANE (0.55) ALDH1A1KDM4EELANEMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5238983-A None JP disclosed
JP-H05238983-A ANTIMICROBIAL AGENT NIPPON OIL & FATS CO LTD 1993-09-17 JP disclosed