SCHEMBL9559214

SCHEMBL9559214

O=S(=O)(c1ccc(O)cc1)c1ccc(OCC(O)COc2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
CA9 Q16790 5/20 0.51
CA7 P43166 3/20 0.51
CA4 P22748 2/20 0.51
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
ADRB1 P08588 7/20 0.49
ADRB2 P07550 5/20 0.49
ADRB3 P13945 5/20 0.49
ALDH1A1 P00352 1/20 0.49
CA12 O43570 3/20 0.48
BACE1 P56817 1/20 0.48
KDM4E B2RXH2 1/20 0.47
PTGS1 P23219 1/20 0.47
SLC6A2 P23975 1/20 0.47
CYP2D6 P10635 1/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14546246 0.94 CA1 (0.56) CA1CA2CA9CA7CA4
SCHEMBL1395596 0.94 GAA (0.56) CA1CA2CA9CA7CA4
SCHEMBL51473 0.94 GAA (0.56) CA1CA2CA9CA7CA4
SCHEMBL1836005 0.87 GAA (0.53) CA1CA2CA9CA7CA4
SCHEMBL9018776 0.85 CA1 (0.51) CA1CA2CA9CA7CA4
SCHEMBL10894645 0.84 PKM (0.56) CA1CA2CA9CA7CA4
SCHEMBL1395595 0.82 PTGS1 (0.48) CA1CA2CA9CA7CA4
SCHEMBL1793032 0.81 CA1 (0.50) CA1CA2CA9CA7CA4
SCHEMBL1792769 0.81 CA1 (0.43) CA1CA2CA9CA7CA4
SCHEMBL12311421 0.80 MEN1 (0.69) CA1CA2CA9CA7CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5246924-A None JP disclosed
JP-H05246924-A PRODUCTION OF 2-PROPANOL COMPOUND NIPPON SODA CO LTD 1993-09-24 JP disclosed