SCHEMBL9559692

SCHEMBL9559692

CCOc1ccc(-c2[c]ccc(OCC)c2-c2ccc(F)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NQO1 P15559 1/20 0.39
MAPT P10636 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CACNA2D1 P54289 1/20 0.38
SSTR5 P35346 3/20 0.37
MAOB P27338 1/20 0.36
KCNH2 Q12809 2/20 0.36
CHRNA7 P36544 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9559649 0.93 NQO1 (0.45) CYP1A2CYP2D6CYP2C19TDP1TSHR
SCHEMBL9559552 0.89 L3MBTL1 (0.43) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559601 0.87 TDP1 (0.41) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559608 0.87 TDP1 (0.41) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559577 0.87 NPC1 (0.46) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559852 0.86 MAPT (0.43) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559646 0.86 MAPT (0.43) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559575 0.86 HPGD (0.44) TSHRHSD17B10NQO1MAPTCACNA2D1
SCHEMBL9559674 0.81 CYP1A2 (0.42) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL9559602 0.78 NPC1 (0.44) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5235061-A 2,4-disilaalkanes; agriculture KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1993-08-10 US disclosed