Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249417 | 1.00 | SIGMAR1 (0.55) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL9245700 | 1.00 | SIGMAR1 (0.55) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL1478014 | 0.98 | SIGMAR1 (0.52) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL430012 | 0.91 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL27820823 | 0.85 | MEN1 (0.51) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL5853429 | 0.83 | TRPV1 (0.53) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL5855428 | 0.83 | TRPV1 (0.53) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL10597706 | 0.83 | TRPV1 (0.53) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL5853432 | 0.83 | TRPV1 (0.53) | SIGMAR1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL5854280 | 0.83 | TRPV1 (0.53) | SIGMAR1L3MBTL1MAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1556706-B | Thieno- (1,3) -oxazin-4-ones with lipase inhibitory activity | ALIZYME THERAPEUTICS LTD | 2011-04-27 | — | — | CN | claimed |
| CN-1556706-A | Thieno- (1,3) -oxazin-4-ones with lipase inhibitory activity | ��Ĭ���ѧ | 2004-12-22 | — | — | CN | claimed |
| CN-1059521-A | The method and the intermediate that prepare 2-hydroxyl-3-thioether-3 phenylpropionic acid | SMITHKLINE BEECHAM CO (US) | 1992-03-18 | — | — | CN | claimed |
| CN-1008091-B | Process for preparing leukotriene antagonists | SMITHKLINE BECKMAN CORP (US) | 1990-05-23 | — | — | CN | claimed |
| CN-1007151-B | Leukotriene antagonists | SMITHKLINE BECKMAN CORP (US) | 1990-03-14 | — | — | CN | claimed |
| CN-1030074-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORP (US) | 1989-01-04 | — | — | CN | claimed |
| CN-86102482-A | Process for preparing leukotriene antagonists | — | 1987-02-04 | — | — | CN | claimed |
| CN-85100811-A | The antagonistic preparation method of leukotriene | — | 1986-07-09 | — | — | CN | claimed |
| CN-101525745-B | Metal surface treatment agent and printed wiring board with protecting film formed thereby | UNIV SICHUAN | 2011-03-30 | — | — | CN | disclosed |
| CN-101525745-A | Metal surface treatment agent and printed wiring board with protecting film formed thereby | UNIV SICHUAN | 2009-09-09 | — | — | CN | disclosed |
| CN-1654709-A | Surface treatment agents for metal films of printed circuit boards | TAMURA KAKEN CORP (JP) | 2005-08-17 | — | — | CN | disclosed |
| CN-1025564-C | Process for the preparation of phenyl epoxy hydroxy acid esters | SMITHKLINE BECKMAN CORP (US) | 1994-08-03 | — | — | CN | disclosed |
| CN-1078229-A | The method and the intermediate that prepare the 2-substituted benzaldehyde | SMITHKLINE BEECHAM CORP (US) | 1993-11-10 | — | — | CN | disclosed |
| EP-0358240-B1 | INTERMEDIATES FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-09 | — | — | EP | disclosed |
| US-4820719-A | ANTIALLERGENS, ANTIINFLAMMATORY, ANTIISCHEMIC AND HYPOTENSIVE AGENTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |
| CN-1030074-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BECKMAN CORP (US) | 1989-01-04 | — | — | CN | disclosed |
| CN-86102482-A | Process for preparing leukotriene antagonists | — | 1987-02-04 | — | — | CN | disclosed |
| EP-0202759-A2 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1986-11-26 | — | — | EP | disclosed |
| CN-85100811-A | The antagonistic preparation method of leukotriene | — | 1986-07-09 | — | — | CN | disclosed |
| US-4548975-A | PHENOLIC ANTIOXIDANT AND DIALKYL PHENYL PHOSPHITE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-22 | — | — | US | disclosed |