Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561464 | 0.91 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9561450 | 0.91 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9559976 | 0.91 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560196 | 0.88 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9559989 | 0.88 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARAPPARGBID | |
| SCHEMBL9560190 | 0.88 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARAPPARGBID | |
| SCHEMBL9560087 | 0.88 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1PPARAPPARGBID | |
| SCHEMBL9158808 | 0.81 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560029 | 0.81 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1 | |
| SCHEMBL9864623 | 0.81 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358240-B1 | INTERMEDIATES FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-09 | — | — | EP | claimed |