Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559976 | 1.00 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARAPPARGMEN1 | |
| SCHEMBL9561450 | 1.00 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARAPPARGMEN1 | |
| SCHEMBL9560041 | 0.91 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1PPARAPPARGTHRA | |
| SCHEMBL9560080 | 0.88 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560376 | 0.83 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1 | |
| SCHEMBL9507481 | 0.83 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561606 | 0.83 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PPARAPPARGBID | |
| SCHEMBL10435617 | 0.82 | PPARG (0.45) | CYSLTR2CYSLTR1PPARAPPARGALDH1A1 | |
| SCHEMBL9559832 | 0.82 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560372 | 0.82 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189226-A | Chemical intermediate for diacid | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0365149-A2 | Leukotriene antagonist prodrugs | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |