Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505649 | 0.85 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LTB4RALDH1A1HPGD | |
| SCHEMBL10431544 | 0.83 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1ALDH1A1HPGDKMT2A | |
| SCHEMBL29090154 | 0.81 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1LTB4RBIDBCL2L1 | |
| SCHEMBL9155578 | 0.79 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9155567 | 0.79 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9386199 | 0.78 | CYSLTR2 (0.98) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9856295 | 0.76 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1MAPTRXFP1BID | |
| SCHEMBL9856152 | 0.76 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1MAPTRXFP1BID | |
| SCHEMBL9560053 | 0.76 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R | |
| SCHEMBL6449278 | 0.76 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1MAPTRXFP1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358240-B1 | INTERMEDIATES FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-09 | — | — | EP | claimed |