Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560959 | 1.00 | MAPT (0.47) | MAPTUSP2TSHRRARBLMNA | |
| SCHEMBL9560341 | 1.00 | MAPT (0.47) | MAPTUSP2TSHRRARBLMNA | |
| SCHEMBL9560511 | 0.95 | MAPT (0.41) | MAPTUSP2TSHRRARBLMNA | |
| SCHEMBL9560422 | 0.92 | RARB (0.47) | MAPTUSP2TSHRRARBALDH1A1 | |
| SCHEMBL9560583 | 0.92 | RARB (0.47) | MAPTUSP2TSHRRARBALDH1A1 | |
| SCHEMBL9560590 | 0.92 | RARB (0.47) | MAPTUSP2TSHRRARBALDH1A1 | |
| SCHEMBL9560963 | 0.92 | MAPT (0.50) | MAPTUSP2TSHRLMNAPOLB | |
| SCHEMBL9560629 | 0.92 | MAPT (0.50) | MAPTUSP2TSHRLMNAPOLB | |
| SCHEMBL9560563 | 0.92 | MAPT (0.50) | MAPTUSP2TSHRLMNAPOLB | |
| SCHEMBL9561004 | 0.91 | RARB (0.48) | MAPTUSP2TSHRRARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |