Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560963 | 1.00 | MAPT (0.50) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560629 | 1.00 | MAPT (0.50) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560346 | 0.95 | POLB (0.45) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560959 | 0.92 | MAPT (0.47) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560341 | 0.92 | MAPT (0.47) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560410 | 0.92 | MAPT (0.47) | MAPTUSP2TSHRPOLBLMNA | |
| SCHEMBL9560590 | 0.89 | RARB (0.47) | MAPTUSP2TSHRALDH1A1MEN1 | |
| SCHEMBL9560583 | 0.89 | RARB (0.47) | MAPTUSP2TSHRALDH1A1MEN1 | |
| SCHEMBL9560422 | 0.89 | RARB (0.47) | MAPTUSP2TSHRALDH1A1MEN1 | |
| SCHEMBL9561004 | 0.88 | RARB (0.48) | MAPTUSP2TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0300009-A1 | LIQUID CRYSTALLINE MIXTURE. | MERCK PATENT GMBH (DE) | 1989-01-25 | — | — | EP | disclosed |
| WO-1988005803-A1 | LIQUID CRYSTALLINE MIXTURE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-08-11 | — | — | WO | disclosed |