Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560557 | 0.99 | RARB (0.50) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560422 | 0.96 | RARB (0.47) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560583 | 0.96 | RARB (0.47) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560590 | 0.96 | RARB (0.47) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560271 | 0.95 | RARB (0.48) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560297 | 0.95 | RARB (0.48) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9561004 | 0.95 | RARB (0.48) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL13253013 | 0.92 | MAPT (0.47) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560511 | 0.92 | MAPT (0.41) | RARBRARAMAPTMEN1ALDH1A1 | |
| SCHEMBL9560710 | 0.89 | RARB (0.53) | RARBRARAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |