Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560603 | 1.00 | MAPT (0.46) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560513 | 1.00 | MAPT (0.46) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560635 | 0.96 | RARB (0.42) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560280 | 0.93 | RARB (0.51) | MAPTUSP2TSHRRARBSMN1; SMN2 | |
| SCHEMBL9560374 | 0.93 | RARB (0.51) | MAPTUSP2TSHRRARBSMN1; SMN2 | |
| SCHEMBL9560736 | 0.93 | RARB (0.51) | MAPTUSP2TSHRRARBSMN1; SMN2 | |
| SCHEMBL9560604 | 0.93 | MAPT (0.48) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560741 | 0.93 | MAPT (0.48) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560858 | 0.93 | MAPT (0.48) | MAPTUSP2TSHRRARBTHRB | |
| SCHEMBL9560767 | 0.92 | RARB (0.53) | MAPTUSP2TSHRRARBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |