Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560603 | 0.96 | MAPT (0.46) | RARBMAPTUSP2TSHRTHRB | |
| SCHEMBL9560607 | 0.96 | MAPT (0.46) | RARBMAPTUSP2TSHRTHRB | |
| SCHEMBL9560513 | 0.96 | MAPT (0.46) | RARBMAPTUSP2TSHRTHRB | |
| SCHEMBL9560710 | 0.93 | RARB (0.53) | RARBMAPTUSP2TSHRSMN1; SMN2 | |
| SCHEMBL9560288 | 0.92 | MAPT (0.42) | RARBMAPTUSP2TSHRTHRB | |
| SCHEMBL9560562 | 0.92 | RARB (0.55) | RARBMAPTUSP2TSHRSMN1; SMN2 | |
| SCHEMBL9560697 | 0.92 | RARB (0.55) | RARBMAPTUSP2TSHRSMN1; SMN2 | |
| SCHEMBL9560280 | 0.89 | RARB (0.51) | RARBMAPTUSP2TSHRSMN1; SMN2 | |
| SCHEMBL9560736 | 0.89 | RARB (0.51) | RARBMAPTUSP2TSHRSMN1; SMN2 | |
| SCHEMBL9560374 | 0.89 | RARB (0.51) | RARBMAPTUSP2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |