Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747164 | 0.91 | LTA4H (0.41) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL9560742 | 0.88 | LTA4H (0.40) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL9560684 | 0.88 | LTA4H (0.40) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL10865464 | 0.83 | LTA4H (0.40) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL9714669 | 0.82 | LTA4H (0.41) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL10360884 | 0.81 | LTA4H (0.41) | LTA4HMAPK1KCNH2MAPTLMNA | |
| SCHEMBL9714162 | 0.81 | LTA4H (0.39) | LTA4HMAPK1KCNH2MAPTL3MBTL1 | |
| SCHEMBL9714661 | 0.81 | LTA4H (0.39) | LTA4HMAPK1MAPTL3MBTL1LMNA | |
| SCHEMBL9560443 | 0.79 | LTA4H (0.48) | LTA4HMAPK1MAPTL3MBTL1LMNA | |
| SCHEMBL9560885 | 0.79 | LTA4H (0.42) | LTA4HMAPK1KCNH2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |