Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.43 |
| ▸ | CES1 | P23141 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076741 | 0.88 | FAAH (0.44) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL28446924 | 0.87 | FAAH (0.46) | FAAHCES1CES2DGKAMEN1 | |
| Hydrochloric Acid SCHEMBL4840902 | 0.85 | FAAH (0.44) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL28898098 | 0.85 | FAAH (0.47) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL28454736 | 0.85 | FAAH (0.47) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL9494915 | 0.83 | FAAH (0.42) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL10526294 | 0.83 | FAAH (0.42) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL9495517 | 0.83 | FAAH (0.42) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL9494410 | 0.83 | FAAH (0.42) | FAAHCES1CES2DGKAMEN1 | |
| SCHEMBL9495532 | 0.81 | FAAH (0.41) | FAAHCES1CES2DGKAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |