Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560708 | 1.00 | DGKA (0.49) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560506 | 0.98 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560913 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9615328 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560361 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560509 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560266 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560655 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560620 | 0.94 | DGKA (0.46) | DGKAMAPTLMNAALDH1A1PAM | |
| SCHEMBL9560268 | 0.94 | DGKA (0.40) | DGKAMAPTLMNAALDH1A1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |