Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 19/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561433 | 0.89 | HPRT1 (0.45) | HPRT1PNP | |
| SCHEMBL9561047 | 0.85 | ADCY5 (0.35) | — | |
| SCHEMBL10534207 | 0.85 | HPRT1 (0.39) | HPRT1PNP | |
| SCHEMBL9561407 | 0.82 | HPRT1 (0.39) | HPRT1PNP | |
| SCHEMBL8465859 | 0.78 | ADCY5 (0.47) | — | |
| SCHEMBL8466600 | 0.78 | ADCY5 (0.47) | — | |
| SCHEMBL29769282 | 0.77 | HPRT1 (0.45) | HPRT1PNP | |
| SCHEMBL8466911 | 0.76 | ADCY5 (0.37) | — | |
| SCHEMBL8464129 | 0.76 | CYP1A2 (0.42) | — | |
| SCHEMBL9001206 | 0.76 | MAPT (0.36) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | disclosed |