Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561311 | 1.00 | LTA4H (0.44) | LTA4HALDH1A1TDP1CETPFFAR1 | |
| SCHEMBL10713301 | 1.00 | LTA4H (0.44) | LTA4HALDH1A1TDP1CETPFFAR1 | |
| SCHEMBL9561289 | 0.85 | LTA4H (0.48) | LTA4HCETPFFAR1ACACBACACA | |
| SCHEMBL9561286 | 0.85 | LTA4H (0.48) | LTA4HCETPFFAR1ACACBACACA | |
| SCHEMBL9561389 | 0.85 | LTA4H (0.48) | LTA4HALDH1A1CETPFFAR1ACACB | |
| SCHEMBL9561393 | 0.85 | LTA4H (0.48) | LTA4HALDH1A1CETPFFAR1ACACB | |
| SCHEMBL9561453 | 0.84 | LTA4H (0.47) | LTA4HCETPFFAR1ACACBACACA | |
| SCHEMBL9561461 | 0.84 | LTA4H (0.47) | LTA4HCETPFFAR1ACACBACACA | |
| SCHEMBL9804514 | 0.82 | LTA4H (0.45) | LTA4HALDH1A1TDP1CETPFFAR1 | |
| SCHEMBL9804659 | 0.77 | LTA4H (0.49) | LTA4HALDH1A1CETPFFAR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0276558-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-08 | — | — | EP | disclosed |
| EP-0276558-A2 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-03 | — | — | EP | disclosed |