Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 11/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 11/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560372 | 0.87 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560302 | 0.86 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560229 | 0.84 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560080 | 0.83 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1 | |
| SCHEMBL9507481 | 0.82 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559832 | 0.81 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9559976 | 0.80 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9561450 | 0.80 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9561464 | 0.80 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARATHRATHRB | |
| SCHEMBL9560376 | 0.78 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189226-A | Chemical intermediate for diacid | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0365149-A2 | Leukotriene antagonist prodrugs | SMITHKLINE BEECHAM CORPORATION (US) | 1990-04-25 | — | — | EP | disclosed |