Lithium Ion

Lithium Ion

SCHEMBL9561329

CC(C)C[Al](C)CC(C)C.[H-].[Li+]

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4385947 0.93 TSHR (0.31) TSHR
SCHEMBL9561331 0.89
Methyl Alcohol SCHEMBL28412835 0.86 TSHR (0.35) TSHR
Lithium Ion SCHEMBL9201740 0.74 ALDH1A1 (0.32) ALDH1A1TSHRMAPK1
SCHEMBL728051 0.69
SCHEMBL29035941 0.67
SCHEMBL1901191 0.67
Lithium Ion SCHEMBL7059606 0.65
SCHEMBL3819026 0.65 TSHR (0.33) TSHR
SCHEMBL15141 0.65 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254277-B1 OLIGOMERIZATION CATALYST AND OLIGOMERIZATION PROCESS UNION CARBIDE CORPORATION (US) 1993-03-17 EP disclosed
US-4822915-A METAL COMPLEXES AS POLYMERIZATION CATALYST FOR THE OLIGOMERIZATION OF ETHYLENE; CATALYST SELECTIVITY UNION CARBIDE CORPORATION (US) 1989-04-18 US disclosed
EP-0254277-A2 Oligomerization catalyst and oligomerization process UNION CARBIDE CORPORATION (US) 1988-01-27 EP disclosed
US-4716138-A REACTION PRODUCT OF TRANSITION METAL COMPOUND AND ORGANOPHOSPHORUS SULFONATE UNION CARBIDE CORPORATION (US) 1987-12-29 US disclosed
US-4689437-A ETHYLENE OR ETHYLENE-PROPYLENE, CATALYST FROM TRANSITION METAL COMPOUND, ACTIVATOR, ORGANOPHOSPHORUS SULFONATE LIGAND UNION CARBIDE CORPORATION (US) 1987-08-25 US disclosed
US-4127658-A ANTIINFLAMMATORY SANDOZ, INC. (US) 1978-11-28 US disclosed
US-4100300-A ANTIINFLAMMATORY, TRANQUILIZER SANDOZ, INC. (US) 1978-07-11 US disclosed
US-4032580-A ANTI-INFLAMMATORY 1-PHENYL-2,3-BUTADIEN-1-OLS, METHODS OF USE AND COMPOSITIONS CONTAINING SAME SANDOZ, INC. (US) 1977-06-28 US disclosed
US-3997574-A PROGESTATIONAL AGENT SANDOZ, INC. (US) 1976-12-14 US disclosed
US-3997664-A STEROIDS, ESTROGENIC, PROGESTATIONAL SANDOZ, INC. (US) 1976-12-14 US disclosed
US-3978048-A PROGESTATIONAL AGENTS SANDOZ, INC. (US) 1976-08-31 US disclosed
US-3969415-A ANTIINFLAMMATORY SANDOZ, INC. (US) 1976-07-13 US disclosed
US-3961053-A STEROIDS, CONTROLLING FERTILITY AND ESTRUS SANDOZ, INC. (US) 1976-06-01 US disclosed
US-3932530-A ANTIINFLAMMATORY AGENTS SANDOZ, INC. (US) 1976-01-13 US disclosed