SCHEMBL9561396

SCHEMBL9561396

C[SiH](C)O[SiH3].FC(F)(F)C(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL9788378 0.71
SCHEMBL65852 0.71
SCHEMBL20752 0.71
SCHEMBL9501082 0.71
SCHEMBL1479028 0.71
SCHEMBL9066678 0.71 ALDH1A1 (0.54) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7951920 0.67
SCHEMBL10522167 0.67
SCHEMBL16671452 0.67
SCHEMBL10320028 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5185089-A Aliphatic hydrogen-containing compound to reduce formation of 1-chloro-2,2,2-trifluoroethane ALLIED-SIGNAL INC. (US) 1993-02-09 US disclosed
US-5108632-A For compression refrigeration and air-conditioning; combining aliphatic non-hydrogen compound, reduces formation of 1-chloro -2,2,2-trifluoroethane ALLIED-SIGNAL INC. (US) 1992-04-28 US disclosed
WO-1991016119-A1 NON-WOVEN ELEMENT COMPRISED OF FIBRID BINDER JAMES RIVER PAPER COMPANY, INC. (US) 1991-10-31 WO disclosed