Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622340 | 0.75 | CES1 (0.42) | TSHRMAPTSMN1; SMN2CES1TDP1 | |
| SCHEMBL3349927 | 0.74 | CYP1A2 (0.52) | TSHRMAPTSMN1; SMN2CES1TDP1 | |
| SCHEMBL3345524 | 0.74 | CES1 (0.50) | TSHRKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL3349207 | 0.74 | CES1 (0.45) | TSHRKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL8689493 | 0.73 | PPARG (0.35) | KMT2ASMN1; SMN2MAPK1MEN1KDM4E | |
| SCHEMBL10517046 | 0.73 | TSHR (0.63) | TSHRKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL6425252 | 0.71 | TSHR (0.61) | TSHRKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL11142714 | 0.70 | TSHR (0.50) | TSHRKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL3345739 | 0.70 | CES1 (0.46) | TSHRKMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2791083 | 0.70 | TSHR (0.64) | TSHRKMT2AMAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522152-A1 | LHRH ANTAGONISTS | THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5171835-A | LHRH antagonists | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992013883-A1 | LHRH ANTAGONISTS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-08-20 | — | — | WO | disclosed |