Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3349207 | 0.78 | CES1 (0.45) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL3349927 | 0.78 | CYP1A2 (0.52) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL3345524 | 0.78 | CES1 (0.50) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL3349906 | 0.76 | TDP1 (0.45) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL9561521 | 0.75 | TSHR (0.47) | CES1TDP1L3MBTL1LMNATSHR | |
| SCHEMBL3349186 | 0.74 | TDP1 (0.44) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL3345510 | 0.74 | CES1 (0.45) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL3345739 | 0.74 | CES1 (0.46) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL8251886 | 0.73 | TDP1 (0.47) | CES1TDP1L3MBTL1CES2LMNA | |
| SCHEMBL9756273 | 0.72 | CES1 (0.45) | CES1TDP1L3MBTL1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171835-A | LHRH antagonists | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-12-15 | — | — | US | disclosed |