Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 8/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27887971 | 0.79 | FAAH (0.48) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL6016882 | 0.78 | FAAH (0.44) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL6016888 | 0.76 | FAAH (0.48) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL10380718 | 0.72 | FAAH (0.48) | KMT2AFAAHCES1CES2MEN1 | |
| SCHEMBL23581967 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 | |
| SCHEMBL17203939 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 | |
| SCHEMBL5936931 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 | |
| SCHEMBL17204170 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 | |
| SCHEMBL15649886 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 | |
| SCHEMBL15649706 | 0.72 | GRIK1 (0.56) | KMT2AMAPTMEN1HSD17B10HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522152-A1 | LHRH ANTAGONISTS | THE ADMINISTRATORS OF THE TULANE UNIVERSITY EDUCATIONAL FUND (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5171835-A | LHRH antagonists | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-12-15 | — | — | US | disclosed |
| WO-1992013883-A1 | LHRH ANTAGONISTS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1992-08-20 | — | — | WO | disclosed |