Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.31 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049239 | 0.86 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL7646983 | 0.84 | GSR (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL15756564 | 0.83 | RNPEP (0.44) | FOLH1RNPEPFNTAFNTBANPEP | |
| SCHEMBL7586373 | 0.78 | SLC7A5 (0.39) | SLC7A5SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL7588933 | 0.77 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1FOLH1 | |
| SCHEMBL7586237 | 0.75 | RNPEP (0.38) | FOLH1RNPEPFNTAFNTBBHMT | |
| SCHEMBL27639943 | 0.75 | GSR (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL1674768 | 0.75 | GSR (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL8053434 | 0.75 | RNPEP (0.40) | SLC1A3SLC1A2SLC1A1FOLH1RNPEP | |
| SCHEMBL19974077 | 0.74 | ANPEP (0.51) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| US-5110798-A | Immunomodulators for bone marrow transplants | CO PHARMA CORPORATION S.R.L. (IT) | 1992-05-05 | — | — | US | disclosed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | disclosed |