Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1877573 | 1.00 | ZDHHC2 (0.51) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL6663437 | 1.00 | ZDHHC2 (0.51) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL11884624 | 0.87 | ZDHHC2 (0.48) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL17138146 | 0.87 | KMT2A (0.47) | ZDHHC2HTR1AKMT2AMEN1KDM4E | |
| SCHEMBL17138147 | 0.87 | KMT2A (0.47) | ZDHHC2HTR1AKMT2AMEN1KDM4E | |
| SCHEMBL6662256 | 0.85 | ZDHHC2 (0.52) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL6662253 | 0.85 | ZDHHC2 (0.52) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL10954131 | 0.82 | ZDHHC2 (0.57) | ZDHHC2HTR1AKMT2AMAPTALDH1A1 | |
| SCHEMBL1885125 | 0.82 | ZDHHC2 (0.57) | ZDHHC2HTR1AKMT2AMAPTALDH1A1 | |
| SCHEMBL27320033 | 0.81 | AKT1 (0.62) | ZDHHC2HTR1AKMT2AMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189182-A | Catalytic cyclization | BASF AKTIENGESELLSCHAFT (DE) | 1993-02-23 | — | — | US | disclosed |
| EP-0306875-A2 | Process for the preparation of 5-methyl butyrolactone | BASF Aktiengesellschaft (DE) | 1989-03-15 | — | — | EP | disclosed |
| US-4791220-A | HEATING WITH AMINE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-13 | — | — | US | disclosed |