Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561676 | 1.00 | ZDHHC2 (0.51) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL1877573 | 1.00 | ZDHHC2 (0.51) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL11884624 | 0.87 | ZDHHC2 (0.48) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL17138146 | 0.87 | KMT2A (0.47) | ZDHHC2HTR1AKMT2AMEN1KDM4E | |
| SCHEMBL17138147 | 0.87 | KMT2A (0.47) | ZDHHC2HTR1AKMT2AMEN1KDM4E | |
| SCHEMBL6662256 | 0.85 | ZDHHC2 (0.52) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL6662253 | 0.85 | ZDHHC2 (0.52) | ZDHHC2HTR1AKMT2AMAOBMEN1 | |
| SCHEMBL10954131 | 0.82 | ZDHHC2 (0.57) | ZDHHC2HTR1AKMT2AMAPTALDH1A1 | |
| SCHEMBL1885125 | 0.82 | ZDHHC2 (0.57) | ZDHHC2HTR1AKMT2AMAPTALDH1A1 | |
| SCHEMBL27320033 | 0.81 | AKT1 (0.62) | ZDHHC2HTR1AKMT2AMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118998-A | Preparation method of CETP inhibitor Obicetrapib (AMG-899) | 上海相辉医药科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-119118998-A | Preparation method of CETP inhibitor Obicetrapib (AMG-899) | 上海相辉医药科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | HENKEL AG & CO. KGAA (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | HENKEL AG & CO. KGAA (DE) | 2018-05-24 | — | — | US | disclosed |
| CN-102114433-B | Supported arsine catalyst as well as synthesizing method and application thereof in Wittig reaction | SHANGHAI INST ORGANIC CHEM | 2013-06-19 | — | — | CN | disclosed |
| CN-102114433-A | Supported arsine catalyst as well as synthesizing method and application thereof in Wittig reaction | SHANGHAI INST ORGANIC CHEM | 2011-07-06 | — | — | CN | disclosed |
| EP-1123915-B1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | NIPPON CATALYTIC CHEM IND (JP) | 2004-07-28 | — | — | EP | disclosed |
| US-6541656-B2 | Reacting an alpha, beta unsaturated carboxylic acid ester with a heterocyclic oxygen nitrogen, or sulfur compound | NIPPON SHOKUBAI COMPANY, LTD. (JP) | 2003-04-01 | — | — | US | disclosed |
| US-6342627-B1 | ESTER INTERCHANGE WITH ALCOHOL IN THE PRESENCE OF LANTHANOIDE METAL ALKOXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-29 | — | — | US | disclosed |
| EP-0353935-A1 | Ethylene alpha-olefin polymer substituted mono-and dicarboxylic acid lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0336664-A2 | Improved dispersant additives derived from amido-amine adducts | EXXON CHEMICAL PATENTS INC. (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4857217-A | ADDUCT OF POLYOLEFIN MODIFIED WITH AN ACID AND POLYAMINE MODIFIED WITH (THIO)AMIDO COMPOUND | EXXON CHEMICAL PATENTS INC. (US) | 1989-08-15 | — | — | US | disclosed |
| US-4845269-A | Preparation of 3-pentenoates from 2-pentenoates | BASF AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0319229-A2 | Improved dispersant additives derived from amido-amines | EXXON CHEMICAL PATENTS INC. (US) | 1989-06-07 | — | — | EP | disclosed |
| EP-0125641-B1 | ALKANOYLOXYBENZENESULFONATE SALT PRODUCTION | ETHYL CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4588533-A | REACTING PHENYL ESTER OF ORGANIC ACID AND SULFUR TRIOXIDE | ETHYL CORPORATION (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0165480-A1 | Method of preparing acyloxybenzenesulfonic acids and salts thereof | ETHYL CORPORATION (US) | 1985-12-27 | — | — | EP | disclosed |
| US-4537724-A | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0125641-A2 | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10251826-B2 | Alkaline agent for lightening hair containing oxidants and special carboxylic acid esters | KRT18, ALDH7A1, ALDH1A2 | ZDHHC2 1129/4885HTR1A 4027/4885KMT2A 805/4885 |
| US-20180140523-A1 | ALKALINE AGENT FOR LIGHTENING HAIR CONTAINING OXIDANTS AND SPECIAL CARBOXYLIC ACID ESTERS | KRT18, ALDH7A1, ALDH1A2 | ZDHHC2 1129/4885HTR1A 4027/4885KMT2A 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.