Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21197727 | 1.00 | CFB (0.36) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL2190192 | 1.00 | CFB (0.36) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL606913 | 0.94 | CFB (0.39) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL29908655 | 0.94 | CFB (0.39) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL246216 | 0.94 | CFB (0.39) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL606912 | 0.94 | CFB (0.39) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL8207460 | 0.92 | CFB (0.38) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL27866641 | 0.92 | CFB (0.38) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| SCHEMBL9561702 | 0.92 | CFB (0.38) | CFBNR1H2NR1H3OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL28274724 | 0.92 | CFB (0.38) | CFBNR1H2NR1H3OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546069-B | Process improvement method of pregabalin | 广州市桐晖药业有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118546069-A | Process improvement method of pregabalin | 广州市桐晖药业有限公司 | 2024-08-27 | — | — | CN | disclosed |
| US-11512041-B2 | Highly enantioselective access to cyclic beta-amino acids | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-11-29 | — | — | US | disclosed |
| US-20210171436-A1 | HIGHLY ENANTIOSELECTIVE ACCESS TO CYCLIC BETA-AMINO ACIDS | UNIV NANYANG TECH (SG) | 2021-06-10 | — | — | US | disclosed |
| EP-3599246-A1 | MEANS AND METHODS FOR SYNTHESIZING PRECURSORS OF Y-AMINOBUTYRIC ACID (GABA) ANALOGS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-01-29 | — | — | EP | disclosed |
| US-9593071-B2 | Process for the preparation of gamma amino acids and intermediates used in said process | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2017-03-14 | — | — | US | disclosed |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-11 | — | — | US | disclosed |
| EP-2703381-B1 | METHOD FOR PRODUCING FIVE-MEMBERED RING-CONTAINING COMPOUND | ONO PHARMACEUTICAL CO (JP) | 2015-10-21 | — | — | EP | disclosed |
| CN-104220433-A | Process for preparing gamma amino acids and intermediates useful in said process | ROYAL COLLEGE OF SURGEONS IE | 2014-12-17 | — | — | CN | disclosed |
| US-20140336412-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2014-11-13 | — | — | US | disclosed |
| EP-2782911-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | Royal College of Surgeons in Ireland (IE) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013189978-A1 | PROCESS FOR PREPARING ß-AMINO ACID DERIVATIVES AND USE OF SAID PROCESS FOR PREPARING TELAPREVIR | SANDOZ AG (CH) | 2013-12-27 | — | — | WO | disclosed |
| WO-2013076225-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2013-05-30 | — | — | WO | disclosed |
| US-20110172438-A1 | Enantioselective Cascade Michael-Michael Reactions and Related Catalysts | NATIONAL SCIENCE FOUNDATION | 2011-07-14 | — | — | US | disclosed |
| WO-2010027510-A2 | ENANTIOSELECTIVE CASCADE MICHAEL-MICHAEL REACTIONS AND RELATED CATALYSTS | STC. UNM (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172438-A1 | Enantioselective Cascade Michael-Michael Reactions and Related Catalysts | FASN, PTGES, CBS | CFB 4611/4885NR1H2 1592/4885NR1H3 1648/4885 |
| US-11512041-B2 | Highly enantioselective access to cyclic beta-amino acids | BCAT1, BCAT2, SLC7A1 | CFB 2014/4885NR1H2 1002/4885NR1H3 596/4885 |
| US-20210171436-A1 | HIGHLY ENANTIOSELECTIVE ACCESS TO CYCLIC BETA-AMINO ACIDS | BCAT1, BCAT2, SLC7A1 | CFB 2014/4885NR1H2 1002/4885NR1H3 596/4885 |
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | DBH, DDT, CBR3 | CFB 1209/4885NR1H2 577/4885NR1H3 374/4885 |
| US-20140336412-A1 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS | GLRB, GABRP, GABRG1 | CFB 3184/4885NR1H2 1057/4885NR1H3 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.