Ethylene Glycol

Ethylene Glycol

SCHEMBL9562384

C=CC(=O)OCC(CC)OC(=O)C=C.OCCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
HPGD P15428 1/20 0.42
ALDH1A1 P00352 4/20 0.38
TP53 P04637 3/20 0.38
HIF1A Q16665 3/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.37
THRB P10828 1/20 0.36
PRKCA P17252 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537104 0.95 TSHR (0.57) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL18123487 0.84 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL700993 0.83 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL22500806 0.83 ALDH1A1 (0.44) TSHRHPGDALDH1A1PRKCA
SCHEMBL13567626 0.83 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
1,3-Propanediol SCHEMBL11028273 0.82 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL14173057 0.82 TSHR (0.55) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5144261 0.82 HCAR2 (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3139934 0.82 HCAR2 (0.49) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL707088 0.82 TSHR (0.53) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5223353-A Viscoelastic material and nonaqueous electrolyte RICOH COMPANY, LTD. (JP) 1993-06-29 US disclosed