Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749309 | 0.90 | HTR2C (0.51) | MAOBHTR2CSLC6A4SLC6A2TAAR1 | |
| SCHEMBL894468 | 0.84 | GBA1 (0.59) | HTR2CSLC6A4SLC6A2 | |
| SCHEMBL3444214 | 0.83 | MAOB (0.49) | MAOBHRH3 | |
| Hydrochloric Acid SCHEMBL4773715 | 0.83 | GBA1 (0.58) | HTR2CSLC6A4SLC6A2 | |
| SCHEMBL18892649 | 0.83 | EP300 (0.45) | SLC6A4HRH3 | |
| SCHEMBL29706740 | 0.82 | MAOB (0.57) | MAOBTAAR1 | |
| SCHEMBL8307801 | 0.82 | MAOB (0.53) | MAOBSLC6A4SLC6A2HRH3TACR1 | |
| SCHEMBL9178916 | 0.81 | MAOB (0.56) | MAOBSLC6A4SLC6A2TAAR1 | |
| SCHEMBL3361925 | 0.80 | TACR1 (0.49) | HTR2CSLC6A4SLC6A2TACR1 | |
| SCHEMBL1199744 | 0.79 | MAOB (0.53) | MAOBSLC6A4SLC6A2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |
| CN-104876955-A | Inhibitors Of Arginase And Their Therapeutic Applications | MARS INC | 2015-09-02 | — | — | CN | disclosed |
| CN-103068830-A | Arginase inhibitors and therapeutic uses thereof | MARS INC | 2013-04-24 | — | — | CN | disclosed |
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |