Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230781 | 0.89 | TSHR (1.00) | TSHRPOLBRAB9ACYP17A1CYP11B1 | |
| SCHEMBL29622962 | 0.89 | AOC3 (0.67) | TSHRPOLBAOC3RAB9ASMN1; SMN2 | |
| SCHEMBL29622963 | 0.89 | AOC3 (0.67) | TSHRPOLBAOC3RAB9ASMN1; SMN2 | |
| SCHEMBL48610 | 0.82 | TSHR (0.69) | TSHRRAB9ASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL10961901 | 0.81 | PTPN1 (0.70) | POLBAOC3RAB9ASMN1; SMN2HTT | |
| SCHEMBL1902060 | 0.81 | SMN1; SMN2 (0.59) | TSHRPOLBAOC3RAB9ASMN1; SMN2 | |
| SCHEMBL11116153 | 0.81 | SMN1; SMN2 (0.59) | TSHRPOLBAOC3RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11146958 | 0.81 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2HTTL3MBTL1 | |
| Water SCHEMBL11515613 | 0.81 | TSHR (0.67) | TSHRRAB9ASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11748446 | 0.80 | NAMPT (0.73) | TSHRHTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1069491-A | 2-(piperidines-1-yl) alcohol derivative, its method for making and treatment thereof are used | SYNTHELABO (FR) | 1993-03-03 | — | — | CN | disclosed |
| EP-0524846-A1 | 2-(Piperidin-1-yl)ethanol derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-27 | — | — | EP | disclosed |