Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445813 | 1.00 | RIPK1 (0.38) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL9562560 | 1.00 | RIPK1 (0.38) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL9562551 | 1.00 | RIPK1 (0.38) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL15445796 | 0.96 | RIPK1 (0.40) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL24170502 | 0.94 | RIPK1 (0.41) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL9562600 | 0.93 | RIPK1 (0.37) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL15445816 | 0.93 | RIPK1 (0.37) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL9562596 | 0.93 | RIPK1 (0.37) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL9562592 | 0.93 | RIPK1 (0.37) | RIPK1HTR2CHTR2BHTR2APDE4A | |
| SCHEMBL15445814 | 0.92 | RIPK1 (0.36) | RIPK1HTR2CHTR2BHTR2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |